100/100 (Very Low)

OpenClaw： benign
VirusTotal： benign
StaticScan： clean

OpenClaw： benign

The skill and included script implement exactly the advertised sgRNA design behavior (including NCBI fetching) and do not request unrelated credentials or hidden endpoints, though it omits declaring r...

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VirusTotal： benign VT 报告

静态扫描： clean

No suspicious patterns detected.

README 未提供

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        "changelog": "Initial release of crispr-sgrna-designer for precise CRISPR sgRNA design in viral\/microbial genomes, especially high-GC templates.\n\n- Scans target regions for SpCas9 PAMs (NGG and alternatives) with precision.\n- Scores sgRNA candidates using specialized high-GC weighting and modified Rule Set 2 positional logic.\n- Ensures seed-region (12bp) uniqueness to minimize off-target effects.\n- Automatically suggests synonymous donor mutations to prevent re-cutting.\n- Fetches latest genomic references from NCBI for each design session.",
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        "version": "0.1.0"
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        "displayName": "CRISPIR sgRNA Designer",
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        "summary": "Professional-grade CRISPR sgRNA design for viral and microbial genomes, with specialized logic for extreme-GC templates (e.g., Herpesviruses). Use when needi...",
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